ABSTRACT
Objective: To report the first case of using the insulation-tipped diathermic knife 2 [IT knife-2] for the treatment of postintubation tracheal stenosis
Clinical Presentation and Intervention: A 71-year-old female patient with a history of endotracheal intubation 3 years earlier presented with throat discomfort, gross wheezing and dyspnea. Chest imaging and bronchoscopy demonstrated a strand-like tracheal stenosis in the upper trachea. The IT knife-2 was used to treat the patient and the lesion was palliated without complication
Conclusion: This case was successfully treated with the IT knife-2 and thus implies a potential usefulness of the IT knife-2 as a new modality for bronchoscopic intervention
Subject(s)
Humans , Female , Aged , Intubation, Intratracheal , Diathermy , Bronchoscopy , Tomography, X-Ray ComputedABSTRACT
Pulmonary mucoepidermoid carcinoma (MEC) is a rare form of lung cancer that originates from submucosal glands of tracheobronchial tree. Unlike low-grade tumor with benign nature, high-grade case is even rarer and has aggressive clinical features with no definite treatment option. Here, we report a case of high-grade pulmonary MEC with fulminant clinical course. A 74-year-old man presented with cough, sputum and mental change. Chest imaging showed massive mediastinal lymphadenopathy with obstructive pneumonia, and multiple metastases in lung and adrenal gland. Bronchoscopy showed polypoid masses obstructing right main bronchus and bronchus intermedius. Histopathology revealed a mixture of glandular structure lined with mucussecreting cells and nests of squamoid cells with nuclear atypia and pleomorphism, which is compatible with high-grade MEC. We intensively treated the patient with combination antibiotics and ventilator care. However, the patient did not respond to the treatment and rapidly deteriorated, and finally expired a month after diagnosis.
Subject(s)
Aged , Humans , Adrenal Glands , Anti-Bacterial Agents , Bronchi , Bronchoscopy , Carcinoma, Mucoepidermoid , Cough , Diagnosis , Lung , Lung Neoplasms , Lymphatic Diseases , Neoplasm Metastasis , Pneumonia , Sputum , Thorax , Ventilators, MechanicalABSTRACT
Immunoglobulin G4 (IgG4)-related disease is a newly recognized condition characterized by fibroinflammatory lesions with dense lymphoplasmacytic infiltration, storiform-type fibrosis and obliterative phlebitis. The pathogenesis is not fully understood but multiple immune-mediated mechanisms are believed to contribute. This rare disease can involve various organs and pleural involvement is even rarer. We report a case of IgG4-related disease involving pleura. A 66-year-old man presented with cough and sputum production for a week. Chest radiography revealed consolidation and a pleural mass at right hemithorax. Treatment with antibiotics resolved the consolidation and respiratory symptoms disappeared, but the pleural mass was unchanged. Video-assisted thoracoscopic surgery was performed. Histopathology revealed dense lymphoplasmacytic infiltration and storiform fibrosis with numerous IgG4-bearing plasma cells. The serum IgG4 level was also elevated. Further examination ruled out the involvement of any other organ. The patient was discharged without further treatment and there is no evidence of recurrence to date.
Subject(s)
Aged , Humans , Anti-Bacterial Agents , Autoimmune Diseases , Cough , Fibrosis , Immunoglobulin G , Immunoglobulins , Phlebitis , Plasma Cells , Pleura , Pleural Neoplasms , Radiography , Rare Diseases , Recurrence , Sputum , Thoracic Surgery, Video-Assisted , ThoraxABSTRACT
No abstract available.